Assessment of the Utility of Multiparametric Magnetic Resonance Imaging for Initial Detection of Prostate Cancer

BACKGROUND: An accurate diagnosis is essential for the effective treatment of prostate cancer (PCa) and patients’ well-being. AIM: Thе main purpose this study was to assess utility multiparametric magnetic resonance imaging (mp-MRI) initial detection PCa among Bulgarian population men with diseases. MATERIALS AND METHODS: Fifty-three patients, aged 44 82 years, were evaluated clinically significant PCa. Assessment methods included prostate-specific antigen (PSA) serum levels, transrectal ultrasonography (TRUS), GE Discovery 3T MRI, 12-core TRUS biopsy. RESULTS: mp-MRI showed 83.20% concordance biopsy: sensitivity 91.43% (76.90–98.20), specificity 75.00% (34.90–96.80), positive predictive values 94.10% (82.80–98.20) negative 66.70% (38.70–86.40). Of patients classified in imaging–reporting data system (PI-RADS) levels 4 5, 94.12% had biopsy, as well 44.40% PI-RADS level 3. Irrespective age PSA, found be a predictor biopsy (p = 0.009). PSA low (area under curve 0.539; 95% confidence interval [CI]: 0.363–0.712) low, although significant, correlation (rs 0.416; CI: 0.164–0.617). CONCLUSION: According our findings, have high The incorporation into diagnostic pathway can significantly reduce number incorrect diagnoses based on and/or suspicious physical digital examinations.